Ramakrishna Vijayacharya Hosur Padma Shri Awarded In 2014
Ramakrishna Vijayacharya Hosur
Award Name : Padma Shri
Year of Award : 2014
Award for : Science and Engineering
Location : Whitefield, Karnataka, India
Ramakrishna Vijayacharya Hosur is an Indian
biophysical scientist,known for his expertise in the areas of nuclear magnetic
resonance and molecular biophysics. The Government of India honoured him, in
2014, by awarding him the Padma Shri, the fourth highest civilian award, for his
contributions to the fields of science and technology. He was born on 16 May
1953 Karnataka, India. Hosur pioneered research in biomolecular NMR, molecular
biophysics, and biophysical chemistry. He taught courses at TIFR, IIT Bombay
and IIT Roorkee on NMR, mathematics and biophysics. Hosur discovered new
structural motifs in quadruplex DNA structures: A-tetrad, T-tetrad and
C-tetrad; developed new multidimensional NMR pulse sequences; elucidated the
folding hierarchy in HIV-1 protease; developed a novel NMR based theoretical model
for using the very autolytic property - considered to be a hindrance for
structural studies on proteases, to derive the most valuable information on
residue level local unfolding energetics; developed 'scaling techniques' for
sensitivity and resolution enhancement and suggested a pH switch mechanism for
cargo trafficking by DLC8 protein inside living cells.
He also elucidated the native state energy landscape, and
structural and dynamic characteristics of SUMO-1 protein along the equilibrium
folding pathways and demonstrated that the native contacts do not progress
monotonously. Also he elucidated by NMR the self-association pathway of GED
domain of dynamin into a large assembly. He published over 150 research
articles in journals and written and edited several books. He has guided 20 PhD
students. Hosur is the recipient of several awards and honours that include
BRUKER Young Scientist Award (1983), INSA Medal for Young Scientists (1984), BD
Tilak Lecture (1989), BM Birla Award (1992), 3rd Annual Award of Society for
Cancer Research (1998), RK Asundi Memorial Lecture (1998), and Jagdish Shankar
Memorial Lecture (2003) and JC Bose Fellowship (2007-12). He is a Fellow of
Indian Academy of Sciences, Bangalore (1994) and National Academy of Sciences
(India), Allahabad (1997).
